J. Sączewski, Ł. Popenda, J. Fedorowicz In Silico SwissADME Analysis of Antibacterial NHC–Silver Acetates and Halides Complexes.Applied Sciiences2024, 14, 8865.
J. Fedorowicz, J. Sączewski Advances in the Synthesis of Biologically Active Quaternary Ammonium Compounds.International Journal of Molecular Sciences2024, 25, 4649.
J. Fedorowicz, C. D. Cruz, M. Morawska, K. Ciura, S. Gilbert-Girard, L. Mazur, H. Makkyla, P. Ilina, K. Savijoki, A. Fallarero, P. Tammela, J.Sączewski Antibacterial and antibiofilm activity of permanently ionized quaternary ammonium fluoroquinolones.European Journal of Medicinal Chemistry2023, 254, 115373.
K. Ciura, J. Fedorowicz, H. Kapica, M. Pastewska, W. Sawicki, J. Sączewski. Interaction between antifungal isoxazolo[3,4-b]pyridine-3(1H)-one derivatives and human serum proteins analyzed with biomimetic chromatography and QSAR approach.Processes2021, 9, 512.
K. Ciura, J. Fedorowicz, P. Žuvela, M. Lovrić, H. Kapica, P. Baranowski, W. Sawicki, W.M. Wong, J. Sączewski. Affinity of antifungal isoxazolo[3,4-b]pyridine-3(1H)-ones to phospholipids in immobilized artificial membrane (IAM) chromatography.Molecules2020, 25, 4835.
K. Ciura, J. Fedorowicz, H. Kapica, A. Adamkowska, W. Sawicki, J. Sączewski. Affinity of fluoroquinolone-Safirinium dye hybrids to phospholipids estimated by IAM-HPLC.Processes2020, 8, 1148.
K. Ciura, J. Fedorowicz, F. Andrić, P. Žuvela, K.E. Greber, P. Baranowski, P. Kawczak, J. Nowakowska, T. Bączek, J. Sączewski. Lipophilicity determination of antifungal isoxazolo[3,4-b]pyridin-3(1H)-ones and their N1-substituted derivatives with chromatographic and computational methods.Molecules2019, 24, 4311.
J. Fedorowicz, J. Sączewski, A. Konopacka, K. Waleron, D. Lejnowski, K. Ciura, T. Tomašič, Ž. Skok, K. Savijoki, M. Morawska, S. Gilbert-Girard, A. Fallarero. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.European Journal of Medicinal Chemistry2019, 179, 576-590.
K. Ciura, J. Fedorowicz, F. Andrić, K.E. Greber, A. Gurgielewicz, W. Sawicki, J. Sączewski. Lipophilicity determination of quaternary (fluoro)quinolones by chromatographic and theoretical approaches.International Journal of Molecular Sciences2019, 20, 5288.
J. Fedorowicz, J. Sączewski. Modifications of quinolones and fluoroquinolones: hybrid compounds and dual-action molecules. Mon. Chem. 2018, 149, 1199-1245.
A. Makowska, F. Sączewski, P.J. Bednarski, J. Sączewski, Ł. Balewski. Hybrid molecules composed of 2,4-diamino-1,3,5-triazines and 2-imino-coumarins and coumarins. Synthesis and cytotoxic properties. Molecules. 2018, 23, 1616.
A. Kornicka, A. Wasilewska, J. Sączewski, A.L. Hudson, K. Boblewski, A. Lehmann, K. Gzella, M. Belka, F. Sączewski, M. Gdaniec, A. Rybczyńska, T. Bączek. 1-[(Imidazolidin-2-yl)imino]-1H -indoles as new hypotensive agents: synthesis and in vitro and in vivo biological studies.Chemicla Biology and Drug Design2017, 89, 400-410.
L. Strekowski, J. Sączewski, E.A. Raux, N.T. Fernando, J. Klenc, S. Paranjpe, A. Raszkiewicz, A.L. Blake, A.J. Ehalt, S. Barnes, T.C. Baranowski, S.M. Sullivan, G. Satała, A.J. Bojarski. Synthesis and structure-activity relationship analysis of 5-HT7 receptor antagonists : piperazin-1-yl substituted unfused heterobiaryls.Molecules2016, 21, 433.
J. Sączewski, A. Hudson, M. Scheinin, A. Wasilewska, F. Sączewski, A. Rybczyńska, M. Ferdousi, J. M. Laurila, K. Boblewski, A. Lehmann, H. Watts, D. Ma. Transfer of SAR information from hypotensive indazole to indole derivatives acting at α-adrenergic receptors: in vitro and in vivo studies.European Journal of Medicinal Chemistry2016, 115, 406-415.
J. Sączewski, J. Fedorowicz, A. Kędzia, M. Ziółkowska-Klinkosz, A. Jalińska. Synthesis and antifungal activity of some 4,6-dimethylisoxazolo[3,4-b]pyridin-3(1H)-one derivatives.Medicinal chemistry2016, 12, 640-646.
K. Boblewski, A. Lehmann, F. Sączewski, J. Sączewski, A. Kornicka, A. Marchwińska, A. Rybczyńska. Circulatory effect of TCS-80, a new imidazoline compound, in rats.Pharmacological Reports2016, 68, 715-719.
J. Sączewski, A. Hudson, M. Scheinin, A. Rybczynska, D. Ma, F. Sączewski, S. Laird, J. M. Laurila, K. Boblewski, A. Lehmann, J. Gu, H. Watts; Synthesis and biological activities of 2-[(heteroaryl)methyl]imidazolines.Bioorganic and Medicinal Chemistry2012, 20, 108–116.
J. Sączewski, A. Hudson, S. Laird, A. Rybczyńska, K. Boblewski, A. Lehmann, D. Ma, M. Maze, H. Watts, M. Gdaniec N-(Imidazolidin-2-ylidene)-1-arylmethanamine oxides: synthesis, structure and pharmacological evaluation.Archiv der Pharmazie2012, 345, 33–42.
J. Sączewski, A. L. Hudson, A. Rybczyńska 2-[(Arylmethoxy)imino]imidazolidines with potential biological activities.Acta Poloniae Pharmaceutica – Drug Research2009, 66, 671–680.
J. Sączewski, Z. Brzozowski, F. Sączewski, P. J. Bednarski, M. Liebeke, M. Gdaniec; Synthesis and in vitro anti-tumor activity of N-[1-[(3-thioxo-5,6-dihydroimidazo2,1-c[1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene]arylsulfonamides.Bioorganic and Medicinal Chemistry Letters2006, 16, 3663–3667.
F. Sączewski, P. Tabin, R. J. Tyacke, A. Maconie, J. Sączewski, A. Kornicka, D. J. Nutt, A. L. Hudson; 2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic alpha2 receptor ligands.Bioorganic and Medicinal Chemistry2006, 14, 6679–6685.
F. Sączewski, A. Hudson, R. Tyacke, D. Nutt, J. Man, P. Tabin, J. Sączewski; 2-(4,5-Dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I2 imidazoline receptor ligands.European Journal of Pharmaceutical Sciences2003, 20, 201–208.
R. J. Tyacke, F. Sączewski, P. Tabin, J. Sączewski, D. J. Nutt, A. Hudson; Initial evaluation of novel selective ligands for imidazoline2 receptors in rat whole brain.Annals of the New York Academy of Sciences2003, 1009, 357–360.